Rajanala Kaleswara Rao was a popular villainy actor in Telugu films at the time of N.T. Rama Rao. Rajanala Kaleswara Rao was very popular during the mid 50s and the 60s. He was one among the popular actors who hailed from Nellore. He was a theatre artist who won the hearts of the stage drama lovers. Prathigna was his first film, which was released in the year 1953, which was directed by H.M. Reddy. Rajanala Kaleswara Rao was popular for his expressions through the eyes. He was one among the actors who got popular through the body language and not through lengthy dialogues. He followed a style of villainy and maintained it till his last movie. He was the main villain who got the salary for his work that equaled that of the heroes. He performed as the villain for more than 100 films. He was a diabetic patient and due to the high level of diabetics, he got his legs surged. Some of the popular films by Rajanala Kaleswara Rao are Raja Mukutam, Usha Parinayam, Ramudu Bheemudu, Devatha, C.I.D, Farz, Saptaswaralu, Number one and
Hello Brother. Hello Brother is a Telugu version of the film Twin Brother by
Jackie Chan. Nagarjuna, Soundarya and Ramya Krishna did the lead roles. Rajanala Kaleswara Rao acted in this film in a guest role.